Endocrine Abstracts

Introduction: Central precocious puberty (CPP) is a frequent reason for consultation in pediatrics. It is defined as the development of sexual characteristics before the age of 8 years in girls and 9 years in boys. Pediatric pituitary adenomas are rare. We report the case of a patient who presented with central precocious puberty on pituitary adenoma.Observation: This is a patient aged 7 years and 6 months, without any particular history, having consulte...

Introduction: Gayet-Wernicke encephalopathy (WE) is a rare neurological disorder, caused by thiamine (vitamin B1) deficiency. We report a case of tertiary adrenal insufficiency revealing Gayet-Wernicke encephalopathy.Case presentation: A 45-year-old women was admitted with abdominal pain, vomiting and weakness. Her medical history was significant for a long-term self-medication with corticosteroids and chronic vomiting. Clinical examination revealed a cu...

Introduction: Pheochromocytoma (PHEO) is an adrenal medulla tumor secreting catecholamines. Malignancy is defined by the presence of metastases in non-chromaffin tissue. Its optimal management requires experienced multidisciplinary teams.We report the case of a patient followed for malignant pheochromocytomaComment: 58-year-old patient operated for a pheochromocytoma in 2016, then lost sight of. The evolution was marked 6 years later by the installation ...

Introduction: Brown tumors are osteolytic lesions rarely revealing hyperparathyroidism. They result from abnormalities of bone metabolism. They usually occur in the terminal stage of hyperparathyroidism. We report the case of a patient with hyperparathyroidism revealed by a brown tumor.Case: A 39-year-old female patient with no notable medical history who presented for 1 year a mandibular swelling progressively increasing in size after a dental extractio...

Introduction: Primary hyperparathyroidism (PPH) can be complicated by pancreatitis. The frequency of association of primary hyperparathyroidism with pancreatitis is rare, varying between 1.5% and 7%. We report the case of a patient with hyperparathyroidism revealed by acute pancreatitis.Case: A 78-year-old patient, without any particular history, who consulted the emergency room for an acute digestive picture with abdominal pain and bilious vomiting, an ...

Introduction: Lipoatrophy is a rare cutaneous complication in diabetes that presents with localized subcutaneous fat atrophy at the insulin injection site. We report a case of a 62-year-old man type 1 diabetic with lipoatrophy lesions on the thighs.Case report: A 62-year-old male, with clinical history of basedow’s disease, He was diagnosed type 1 diabetes (T1D) when he was 19 years old, treated with premixed human insulin for the last 4 years.His w...

Introduction: Trigger finger is a stenosing tenosynovitis in which constriction of the tendon sheath is associated with the presence of a nodule on the flexor tendon of the finger. This is an often unrecognised complication in the diabetic patient. We report the case of a diabetic patient with a complication of trigger finger.Observation: A 55 year old female patient, known to be diabetic for 10 years and treated with a basal-bolus insulin therapy regime...

Introduction: Familial hypercholesterolemia is an autosomal dominant genetic disease linked to a mutation in 3 genes involved in the catabolism of LDL particles. It is characterized by an exclusive increase in low-density lipoproteins (LDL). It is associated with a high risk of premature cardiovascular complications. We report the case of a patient with familial hypercholesterolemia.Case: 44-year-old patient, From a first-degree consanguineous marriage, ...

Introduction: Growth retardation is considered severe when the height of the child is -3 standard deviation (SD) below the average height in reference to the growth curves of children of the same sex and age. Pituitary stalk interruption syndrome (PSIS) is one of the most common conditions in children with short stature.Case report: We report the case of a 12-years old boy with no clinical history of perinatal injury or traumatic birth, who was admitted ...

Introduction: Primary congenital hypothyroidism is the most common neonatal endocrine disorder, traditionally subdivided into thyroid dysgenesis, referring to a range of abnormalities in thyroid development, and dyshormonogenesis. We report two cases of dyshormonogenesis in a brother and sister followed for congenital hypothyroidism by inactivating mutation of the TSH receptor, illustrating the good evolution in case of an adapted treatment.Clinical case...